PRODUCTION, IMPORT/EXPORT, USE, AND DISPOSAL . Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Class D-2A: Material causing other toxic effects (VERY TOXIC). Tetrachloroethylene. Workplace Hazardous Materials Identification (WHMIS): This product has been classified in accordance with the hazard criteria of the Canadian Controlled Products Regulation (CPR) and the MSDS contains all of the information required by the CPR. Tetrachloroethylene is a nonflammable colorless liquid with a sharp sweet odor; the odor threshold is 1 ppm. 1989 OSHA PEL: 25 ppm (170 mg/m 3) TWA 1993-1994 … Tetrachloroethylene: Overview: EMPLURA ® is our low-cost alternative to high-purity qualities. Tetrachloroethylene is used mainly as a solvent for dry cleaning and metal degreasing. Commercial dry cleaners also use trichloroethylene as a spot remover. R45- May cause cancer. Tetrachloroethylene, also known under the systematic name tetrachloroethene, or perchloroethylene ("perc" or "PERC"), and many other names, is a chlorocarbon with the formula Cl2C=CCl2. Uses advised against Not for food, drug, pesticide or biocidal product use Details of the supplier of the safety data sheet Catalog Number 100964 Product Name Tetrachloroethylene. It is mostly miscible with organic compounds such as alcohol, ether, benzene, etc., and is less soluble in water. (1) The vapor pressure for tetrachloroethylene is 18.47 mm Hg at 25 °C, and it … : C182-20; C182-4 CAS-No 127-18-4 Synonyms Perchloroethylene Recommended Use Laboratory chemicals. It shows IR transparency as it has no C–H bonds making it an ideal solvent for IR spectroscopy. The nerves of the face and head (cranial nerves) may be affected by long-term exposure to trichloroethylene or chemicals formed when it decomposes. 5.1 PRODUCTION Tetrachloroethylene is a commercially important chlorinated hydrocarbon solvent and chemical intermediate. Tetrachloroethylene (127-18-4) WHMIS (Canada) Class D-1B: Material causing immediate and serious toxic effects (TOXIC). Revised on 12/06/2013 Page 6 of 6 16. Safety Data Sheet for Tetrachloroethylene 100964. Tetrachloroethylene has been used medicinally in the past as a general anesthetic, and at high concentrations causes loss of consciousness. TETRACHLOROETHYLENE (PERCHLOROETHYLENE) OSHA PROCESS SAFETY (29 CFR 1910.119): Not regulated. Class D-2A: Material causing other toxic effects (VERY TOXIC). It is given orally in a dose of 0.1 ml/kg up to a maximum of 5 ml as a single dose on an empty stomach. 5. Note: The RfD was derived as a midpoint of two candidate RfDs from studies that reported neurotoxicity in occupationally-exposed adults: 0.0097 mg/kg-day based on changes in reaction time and cognitive effects (Echeverria et al., 1995) and 0.0026 mg/kg-day based on changes in color vision (Cavalleri et al., 1994).See Section I.A.1 of the IRIS Summary for Tetrachloroethylene for … Tetrachloroethylene Tetrachloroethylene is a manufactured chemical used for dry cleaning [1] and metal degreasing. Product Name Tetrachloroethylene. Tetrachloroethylene (127-18-4) WHMIS (Canada) Class D-1B: Material causing immediate and serious toxic effects (TOXIC). PCE is a man-made pollutant which is difficult to degrade. Chemical structure: Tetrachloroethylene-contaminated drinking water in Massachusetts and the risk of colon-rectum, lung, and other cancers. Chiu WA, Jinot J, Scott CS, Makris SL et al. : Mixture SECTION 3 — HAZARDS IDENTIFICATION ***POTENTIAL HEALTH EFFECTS*** ... WHMIS information: D1B (Toxic), D2A (Suspect cancer hazard), D2B (Eye and skin irritant) Tetrachloroethylene (perchloroethylene, PCE), is a chlorinated ethylene compound commonly used as a dry cleaning and degreasing solvent. May harm the nervous system. The recovery of tetrachloroethylene from ceiling samples in 17-day storage tests remained above 100% and 97.3% for charcoal tubes and SKC 575-002 Samplers respectively when the samples were stored at ambient temperatures. It is a heavy liquid that has been used to treat hookworm infection. The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. Product name : Tetrachloroethylene CAS-No. Tetrachloroethylene: incident management. Tetrachloroethylene (casrn 127-18-4) Tetrachloroethylene or perchloroethylene (PCE or PERC) is a non-flammable, colorless volatile liquid with ether-like odor. Class D-2A: Material causing other toxic effects (VERY TOXIC). 2013. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Like most chlorinated solvents, tetrachloroethylene can cause CNS depression. Description of first aid measures First-aid measures after inhalation : If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. Originally thought to possess less hepatotoxicity than chloroform, and without the unpleasant pungency and flammability of ether, Download the identifier in a file. Human health effects of trichloroethylene: key findings and scientific issues. Identification Product Name Tetrachloroethylene Cat No. WHMIS (Canada): CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC). NIOSH. Chronic exposure to tetrachloroethylene may adversely affect the neurologic system and … It is a colorless liquid widely used for dry cleaning of fabrics, hence it is sometimes called "dry-cleaning fluid." (2) Occupational exposure to tetrachloroethylene primarily occurs in industries using the chemical (e.g., many dry cleaning facilities) and at industries manufacturing the chemical. Tetrachloroethylene 127-18-4 100 ppm 25 ppm 60 – 70 Hydrotreated Naphthenic Distillate 64742-53-6 5 mg/m3 5 mg/m3 20 – 30 Bis(tridecyl) Adipate 16958-92-2 5 mg/m3 NE 1 – 5 ... Nations TDG, and WHMIS (Canada) TDG information manuals for details regulations and exceptions covering container sizes, packing ODOR THRESHOLD = 5 to 50 ppm Odor thresholds vary greatly. In tests with rats and mice, i t appeared that tissue destruction or peroxisome prolifera tion rather than genetic mechanisms were the cause of the observed increases in normally occurring cancers. Tetrachloroethylene has been produced commercially since the early 1900s. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. Do not rely on odor alone to determine potentially hazardous exposures. INTERNATIONAL REGULATIONS: Tetrachloroethylene (127-18-4) WHMIS (Canada) Class D-1B: Material causing immediate and serious toxic effects (TOXIC). Studi es have shown that tetrachloroethylene has not caused canc er in exposed workers. Ref: PHE publications gateway number: 2014790 PDF, 265KB, 13 pages. (1) The chemical formula for tetrachloroethylene is C 2 Cl 4, and the molecular weight is 165.83 g/mol. 14. based on extrapolation from inhalation dose-response data. (2) Physical Properties Tetrachloroethylene is a nonflammable colorless liquid with a sharp sweet odor; the odor threshold is 1 ppm. (1) The chemical formula for tetrachloroethylene is C 2 Cl 4 Environ Health Perspect 107(4):265-71. Symptoms may include headaches, fatigue, memory loss, irritability, depression and reduced ability to think or reason. Tetrachloroethylene, also known under the systematic name tetrachloroethene, or perchloroethylene, and many other names (and abbreviations such as "perc" or "PERC", and "PCE"), is a chlorocarbon with the formula Cl2C=CCl2. Tetrachloroethylene found in: Tetrachloroethylene =99.5%, Tetrachloroethylene EMPLURA®, SIAL Tetrachloroethylene, SIAL Tetrachloroethylene, Uvasol®.. Environ Health Perspect 121:303-311. Components on Ingredient List for WHMIS: tetrachloroethylene pentyl acetate EUROPEAN UNION The following information relates to product regulation specific to the directives of the Euopean Union. INTERNATIONAL REGULATIONS: Trichloroethylene, CAS 79-01-6, -EC – yes, Japan – … It is a colorless liquid widely used for dry cleaningof fabrics, hence it is sometimes called "dry-cleaning fluid". 1,1,2,2-Tetrachloroethane is a manufactured, colorless, dense liquid that does not burn easily. Tetrachloroethylene 127-18-4 10 - 30 Chemical Family: Chlorinated Solvent Blend CAS No. Material Safety Data Sheet or SDS for Tetrachloroethylene 100964 from Merck for download or viewing in the browser. Catalog Number 100964. Tetrachloroethylene SDS Safety Data Sheet for Tetrachloroethylene 100964. This file may not be suitable for users of … Current OSHA PEL: 100 ppm TWA, 200 ppm CEILING, 300 ppm 5-minute MAXIMUM PEAK IN ANY 3 HOURS. CAS number: 127–18–4 NIOSH REL: Minimize workplace exposure concentrations; NIOSH considers tetrachloroethylene to be a potential occupational carcinogen as defined by the OSHA carcinogen policy [29 CFR 1990]. Tetrachloroethylene is a chlorinated derivative of a simple hydrocarbon, H 2 C CH 2, in which each of the four hydrogen atoms is replaced by chlorine, Cl 2 C CCl 2. When concentrations in air are high—particularly in closed, poorly ventilated areas—acute exposures can cause dizziness, headache, sleepiness, confusion, nausea, difficulty in speaking and walking, unconsciousness, and death. Respirators and Other Products for Perchloroethylene Exposures in Dry Cleaning A great solution for the dry cleaning industry. Get medical advice/attention if … Limited evidence of a carcinogenic effect. Pioneered by Imperial Chemical Industries in Britain, its development was hailed as an anesthetic revolution. TETRACHLOROETHYLENE: IRRITATION DATA: 810 mg/24 hour(s) skin-rabbit severe; 500 mg/24 hour(s) skin-rabbit mild; 162 mg eyes-rabbit mild; 500 mg/24 hour(s) eyes-rabbit mild TOXICITY DATA: 4100 ppm/6 hour(s) inhalation-rat LC50; >10000 mg/kg skin-rabbit LD50 (Dow); 2629 mg/kg oral-rat LD50 Tetrachloroethylene (CAS No) 127-18-4 97.40 SECTION 4: First-aid measures 4.1. WHMIS Classification: D1B D2A D2B Components on Ingredient List for WHMIS: n-butyl acetate tetrachloroethylene Material Safety Data Sheet or SDS for Tetrachloroethylene 100964 from MilliporeSigma for download or viewing in the browser. It is also used in the manufacture of other chemicals and for textile finishing and dyeing. It is a ground water contaminant which has adverse effect on human health due to its potential toxicity and … Water polluted with tetrachloroethylene may have levels greater than 1 ppm. In soil, background levels are typically 100–1,000 times lower than 1 ppm. However, the background level of tetrachloroethylene in air is usually less than 1 part in 1 billion parts of air (ppb). It is volatile and has a sweet odor. TCE is also used in some household products, such as cleaning wipes, aerosol cleaning products, tool cleaners, paint removers, spray adhesives, and carpet cleaners and spot removers. WHMIS Canada CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC). IUPAC Standard InChIKey: CYTYCFOTNPOANT-UHFFFAOYSA-N. CAS Registry Number: 127-18-4. NFPA HEALTH: 2 HMIS HEALTH: 2 NFPA FLAMMABILITY: 0 HMIS FLAMMABILITY: 0 NFPA REACTIVITY: 0 HMIS REACTIVITY: 0
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